Product Description:
Polymyxin B PB 300µg is an antibiotic produced by Bacillus polymyxa, most commonly utilized for its bactericidal action on Gram-negative bacteria. It is often used for testing the susceptibility of bacteria by using the double disc synergy test and the Kirby-Bauer disk diffusion test. It is approved for use in clinical laboratory settings in the United States. Polymyxin B interferes with the bacterial cell membrane and is an effective agent in the regulation of bacterial growth in both laboratory and clinical environments, and is employed in research, clinical diagnostics, and in drug discovery.
Key Features:
- – Superior Antibiotic: Exhibits potent bactericidal activity against Gram-negative bacteria.
- – Applications: Widely used in microbiology research, clinical diagnostics, and pharmaceutical work.
- – Broader Spectrum: Greater activity against Pseudomonas aeruginosa, Escherichia coli, and other Gram-negative bacteria.
- – High Purity: Can be provided in high-purity formulations for laboratory use.
- – Consistent Performance: Guarantees accurate results in microbiological testing, bacterial susceptibility testing, and preparation of pharmaceutical solutions.
Principle of Polymyxin B PB 300µg:
Polymyxin B primarily binds to the bacterial wall, disrupting the wall as the wall and the membrane of the particles are penetrated, increasing the permeability of the cell wall, and the loss leads to cell death. Its narrow spectrum of activity is mainly limited to Gram-negatives, to which it binds through the lipopolysaccharide (LPS) moiety of the bacterial outer membrane. Polymyxin B works by disrupting the structure of the membrane, causing cellular function and bactericidal action. It is therefore a key antibiotic for the treatment of infections due to Gram-negative organisms.
Applications of Polymyxin B PB 300µg:
- – Antimicrobial Susceptibility Testing: Widely employed in antimicrobial susceptibility testing to identify the efficacy of antibiotics against bacterial isolates.
- – Research and Laboratory Use: Used in research facilities for investigating the structure and functions of bacterial membranes.
- – Clinical Application: Effective against some resistant G-ve bacteria, especially in hospitals.
- – Medicinal Uses: Used in the preparation of topical and injectable drugs for bacterial ailments.
Why Choose Bright-Scientific to Buy Polymyxin B PB 300µg?
- – High Purity and Quality: Produced to high quality control standards, resulting in consistent performance and quality in a variety of research, diagnostic, and discovery applications.
- – Total Laboratory Solutions: Part of our complete line of microbiology products, such as media, reagents, and consumables.
- – Technical Team: If you require guidance with your research, diagnosis, or treatment plans, our in-house technical team will be happy to assist you.
- – Cost-Effective: Polymyxin B is competitively priced, and volume discounts are available for larger orders. We also give attractive prices to our price-sensitive clients in Bangladesh.
Pricing & Availability:
Polymyxin B is available in numerous strengths and preparations. For any information, support, or queries, please contact us or visit our website for discounts on multiple purchases.
Conclusion:
Polymyxin B PB 300µg is a powerful and trusted antibiotic for multiple applications, including clinical diagnostics and pharmaceutical preparations. It plays a crucial role in controlling Gram-negative bacterial infections and in microbiological and pharmaceutical research. High Purity Polymyxin B from Bright Scientific. Bright Scientific offers top-quality Polymyxin B for consistent and reliable performance in the lab and fantastic customer service to meet your laboratory’s requirements.
Contact our sales office or visit our website for quotes or orders.