Chloroform-d 99.96 atom % D – Sigma-Aldrich | Deuterated Solvent for NMR

Product Description

Chloroform-d 99.96 atom % D is a high-purity deuterated solvent manufactured by Sigma-Aldrich for Nuclear Magnetic Resonance (NMR) spectroscopy and advanced analytical research. Also known as Deuterochloroform, Chloroform-d has the molecular formula CDCl₃ and is specifically designed to provide the chemical and isotopic purity required for reliable NMR-based analysis. Sigma-Aldrich lists this product with 99.96 atom % deuterium, an assay of ≥99% (CP), and NMR suitability.

Unlike ordinary chloroform (CHCl₃), Chloroform-d contains deuterium (²H) instead of ordinary hydrogen in the chloroform molecule. This makes it particularly useful as a solvent for NMR spectroscopy, where deuterated solvents are required to provide an appropriate deuterium lock signal and minimize interference from the solvent’s proton signal.

With a molecular weight of 120.38 g/mol and CAS Number 865-49-6, Sigma-Aldrich Chloroform-d is widely applicable in organic chemistry, pharmaceutical research, chemical analysis, spectroscopy, and scientific research laboratories.

Chloroform-d is especially useful for preparing samples for ¹H NMR, ¹³C NMR, and other NMR-based analytical techniques where a deuterated solvent is required. Its high isotopic purity supports reliable spectral analysis and helps researchers identify molecular structures, chemical environments, reaction products, impurities, and compounds in solution.

At Bright Scientific Co., we supply laboratory chemicals and analytical reagents for universities, research laboratories, pharmaceutical companies, chemical industries, quality-control laboratories, and scientific institutions throughout Bangladesh. Customers can contact us for current pricing, availability, and quotation requirements for Sigma-Aldrich Chloroform-d.

What is Chloroform-d?

Chloroform-d, commonly written as CDCl₃, is the deuterated form of chloroform and is one of the commonly used solvents for NMR spectroscopy. In this compound, deuterium replaces the hydrogen atom present in ordinary chloroform.

The use of a deuterated solvent is important in NMR spectroscopy because the deuterium signal can be used by many NMR instruments for the field-frequency lock, helping maintain instrument stability during data acquisition. At the same time, replacing hydrogen with deuterium reduces the intensity of the solvent’s proton contribution compared with ordinary proton-containing solvents.

Sigma-Aldrich identifies Chloroform-d as a deuterated NMR solvent useful in NMR-based research and analyses.

Benefits of Using Sigma-Aldrich Chloroform-d

Sigma-Aldrich Chloroform-d provides the high isotopic purity and chemical quality required for demanding NMR applications. Its 99.96 atom % D isotopic purity makes it suitable for routine and advanced NMR sample preparation.

The solvent is particularly valuable when researchers need a deuterated medium for dissolving organic compounds before NMR analysis. Its established use in analytical chemistry and molecular research makes it suitable for academic, pharmaceutical, chemical, and industrial laboratories.

Key benefits include:

• High isotopic purity of 99.96 atom % D
• Suitable for NMR spectroscopy
• Deuterated solvent for analytical research
• Molecular formula CDCl₃
• Reliable chemical purity
• Suitable for organic compound analysis
• Useful for NMR sample preparation
• Suitable for research and quality-control laboratories
• Available in multiple package sizes
• Manufactured by Sigma-Aldrich

Key Features

• Genuine Sigma-Aldrich Product
• Chloroform-d / Deuterochloroform
• Isotopic Purity: 99.96 atom % D
• Assay: ≥99% (CP)
• Molecular Formula: CDCl₃
• CAS Number: 865-49-6
• Molecular Weight: 120.38 g/mol
• NMR Suitable
• High-Purity Deuterated Solvent
• Suitable for Analytical Chemistry
• Ideal for NMR Sample Preparation
• Suitable for Research Laboratories
• Available in Multiple Packaging Sizes
• Reliable Laboratory Reagent

Technical Specifications

Parameter	Details
Product Name	Chloroform-d
Synonym	Deuterochloroform
Brand	Sigma-Aldrich
Isotopic Purity	99.96 atom % D
Assay	≥99% (CP)
Molecular Formula	CDCl₃
CAS Number	865-49-6
Molecular Weight	120.38 g/mol
Form	Liquid
NMR Suitability	Suitable
Boiling Point	60.9 °C
Melting Point	−64 °C
Density	1.500 g/mL at 25 °C
Refractive Index	n20/D 1.444
Application	NMR Spectroscopy & Analytical Research
Product Number	151823

The specifications above are based on Sigma-Aldrich’s 151823 Chloroform-d listing.

Applications

NMR Spectroscopy

Chloroform-d is primarily used as a deuterated solvent for NMR spectroscopy. It can be used to prepare samples for proton and carbon NMR studies and other NMR-based analytical investigations.

Chemical Research

It is useful in organic chemistry research for dissolving suitable organic compounds prior to spectroscopic characterization. Researchers can use the resulting NMR spectra to investigate molecular structures, chemical environments, reaction products, and compound identity.

Pharmaceutical Research

Chloroform-d can be used in pharmaceutical and medicinal chemistry laboratories for NMR-based characterization of organic molecules, intermediates, and research compounds.

Analytical Laboratories

The solvent is suitable for analytical laboratories performing structural identification and characterization using NMR instrumentation.

Educational & Research Institutions

Universities, research institutes, and academic laboratories can use Chloroform-d for chemistry experiments, spectroscopy training, research projects, and compound characterization.

Quality Control

Chloroform-d can be used in suitable NMR-based quality-control procedures where a deuterated solvent is required for sample preparation and spectral analysis.

NMR Sample Preparation

For NMR analysis, an appropriate quantity of the compound under investigation is dissolved in Chloroform-d and transferred into an NMR tube according to the laboratory’s established procedure.

The deuterated solvent provides the medium required for solution-state NMR measurements while providing deuterium for the instrument’s lock system. The exact solvent volume, sample concentration, and preparation procedure depend on the NMR instrument, probe, compound, and analytical method.

Researchers should always follow their laboratory’s validated NMR sample-preparation procedure and the applicable manufacturer’s instructions.

Physical Properties

Sigma-Aldrich lists Chloroform-d as a liquid with a boiling point of 60.9 °C, melting point of −64 °C, and density of 1.500 g/mL at 25 °C. The listed refractive index is n20/D 1.444.

These physical properties are useful when handling, storing, and preparing samples with the solvent in an analytical laboratory.

Safety & Handling

Chloroform-d is a hazardous laboratory chemical and should be handled only by appropriately trained personnel using suitable laboratory safety procedures.

• Handle in accordance with the applicable Safety Data Sheet (SDS).
• Use appropriate laboratory gloves and eye/face protection.
• Avoid breathing vapors.
• Work in a properly ventilated area or suitable chemical fume hood.
• Avoid unnecessary skin and eye contact.
• Keep the container tightly closed when not in use.
• Store according to the manufacturer’s recommended conditions.
• Keep away from incompatible materials.
• Dispose of unused material and contaminated waste according to applicable laboratory and local regulations.

Sigma-Aldrich lists multiple hazard classifications for its Chloroform-d products, including acute toxicity, skin/eye irritation, carcinogenicity, reproductive toxicity, and repeated-exposure toxicity classifications; the exact classification can vary with the specific formulation and stabilizer. Always consult the SDS for the exact product number being purchased.

Important Note About Chloroform-d Variants

Sigma-Aldrich offers several Chloroform-d formulations. For example, product 151823 is listed as 99.96 atom % D without the TMS formulation described on some other product pages, while other Sigma-Aldrich products contain 0.03%, 0.05%, 0.1%, or 1% TMS, or use other stabilizer configurations.

Therefore, customers should confirm the product number, isotopic purity, TMS content, stabilizer, and package size before ordering when a specific NMR solvent specification is required.

Why Buy from Bright Scientific Co.?

• Genuine Sigma-Aldrich Laboratory Chemicals
• High-Quality Analytical Reagents
• Competitive Pricing
• Bulk Order Facilities Available
• Laboratory Chemical Supply Across Bangladesh
• Suitable for Universities and Research Institutions
• Supply Support for Pharmaceutical & Industrial Laboratories
• Professional Customer Support
• Product Availability Assistance
• Reliable Laboratory Product Sourcing

Chloroform-d Price in Bangladesh

Looking for the Sigma-Aldrich Chloroform-d 99.96 atom % D price in Bangladesh? Contact M/S Bright Scientific Co. for the latest price, package-size availability, and quotation.

Whether you need a small quantity for academic NMR research or a larger package for an analytical or research laboratory, Bright Scientific can provide product availability and quotation information according to your requirements.

Order Chloroform-d from Bright Scientific Co.

Purchase Sigma-Aldrich Chloroform-d 99.96 atom % D from M/S Bright Scientific Co. for NMR spectroscopy, analytical chemistry, organic chemistry research, pharmaceutical research, and laboratory applications.

For product availability, current pricing, package-size options, and bulk requirements, contact Bright Scientific Co. directly.

Official Sigma-Aldrich product information: Sigma-Aldrich Chloroform-d 99.96 atom % D – Product 151823

Contact Information

Bright Scientific Co.

32/1 Shahid Nazrul Islam Sharak, Hatkhola Road, Shuvasca Plaza, Tikatuly, Dhaka-1203, Bangladesh

Phone: +880 1711-285976